INBRAIN and the EIC Accelerator: Graphene Wired to the Brain
INBRAIN Neuroelectronics, a Barcelona company led by CEO and co-founder Carolina Aguilar, develops brain implants made of graphene that record and stimulate neural activity. Its EIC project said current implants are "made of big metal leads with multiple limitations, such as poor resolution, low specificity and high invasiveness", and promised graphene implants that, with AI, could read "single neural cells at a resolution never seen before", according to CORDIS.
The European Innovation Council granted €2,493,750 towards a €3.56 million project from May 2023 to April 2025, focused on a high-resolution cortical interface for brain mapping during surgery. The final report describes three large-animal studies, including a Good Laboratory Practice safety study, which "confirmed the superiority of graphene vs current metal electrodes in signal quality", a move from 4-inch to 6-inch wafer production, and work towards UK regulatory approval for a first-in-human study. In September 2024 INBRAIN announced the world's first human procedure with a graphene-based brain-computer interface, and in October 2024 it closed a $50 million Series B led by imec.xpand with the EIC Fund.
Company file
- Legal entity
- INBRAIN Neuroelectronics S.L., Barcelona
- CEO
- Carolina Aguilar, co-founder
- Products
- Acute cortical interface; chronic implant platform for Parkinson's and other disorders
- Investors
- imec.xpand, EIC Fund, Fond ICO Next Tech, CDTI-Innvierte, Avançsa, Asabys, Aliath, Vsquared
- Partners
- Merck KGaA, Microsoft
- EIC project
- EGNITE, 1 May 2023 to 30 Apr 2025, closed
- EIC funding
- Blended finance; EIC Fund joined Series B
Where INBRAIN Stands Now
INBRAIN's website lists positive interim clinical results in July 2025 showing its graphene interface delivers "neural fidelity beyond conventional materials", and a strategic collaboration with Microsoft on agentic AI for precision neurology in December 2025. The Series B brought total funding since the company's founding to $68 million, and Merck KGaA provided additional funding for applications in its therapeutic areas. The company says the FDA granted Breakthrough Device Designation for its Parkinson's therapy in August 2023 and accepted it into its TAP advisory programme in January 2024.
The record
Graphene brain interface from animal studies to first human
INBRAIN used its EIC project to take its graphene cortical interface through large-animal and GLP safety studies to a first-in-human study approved by the UK regulator. It then raised a $50M Series B with the EIC Fund.
- Oct 2022EIC Accelerator cut-offEGNITEblended finance
- May 2023EIC project starts€3.56M project€2.49M grant
- 2023-24Large-animal studiesThree studies, including GLP safety
- Sep 2024First human procedureGraphene brain-computer interface
- Oct 2024Series BLed by imec.xpand, with the EIC Fund$50M
- Apr 2025EIC project ends510(k) route discussed with FDA
- Jul 2025Interim resultsPositive, per company
- Dec 2025Microsoft collaborationAgentic AI for precision neurology
CORDIS, imec and INBRAIN.
"We're shaping the future of brain-computer interface therapeutics."
Carolina Aguilar, CEO and co-founder, INBRAIN, October 2024The Technology: Graphene Instead of Metal
INBRAIN describes graphene as a Nobel Prize-winning material known for its strength, flexibility and conductivity. Its implant is 10 micrometres thick and uses tiny graphene contacts to record brain signals in fine detail and stimulate precisely. The first product, a temporary interface used during brain surgery, connects to existing CE-marked equipment. The second is a chronic implant for therapies such as Parkinson's disease, epilepsy and speech decoding.
The industrialisation
Wafer size for graphene interface production
During the project INBRAIN moved fabrication from 4-inch to 6-inch wafers as part of industrialisation.
CORDIS project 190141476, report. Values in inches.
What the EIC Project Promised, and What CORDIS Shows
The EIC project
The EU paid 70% of a €3.6M project
The EGNITE project ran from May 2023 to April 2025. CORDIS lists it as closed.
CORDIS project 190141476. Values in € millions.
The project covered development of the acute cortical interface through to human use. The report documents animal and GLP safety studies, industrialisation, and preparation of the first-in-human study, which took place in 2024. It says a revised design would then be validated and submitted to the FDA through the 510(k) route. No FDA clearance has been announced. CORDIS lists the project as closed.
- Large-animal and GLP studiesDeliveredThree studies.
- First human useDeliveredSeptember 2024.
- Industrial fabricationDelivered6-inch wafers.
- FDA clearancePendingNot announced.
The Money
The Series B was led by imec.xpand, with the EIC Fund, Spain's Fond ICO Next Tech and CDTI-Innvierte, and Catalonia's Avançsa among new investors, imec said. The EIC Fund's share and INBRAIN's revenue are not public.
The money
INBRAIN's private funding in US dollars
The Series B was led by imec.xpand with the EIC Fund, Fond ICO Next Tech, CDTI-Innvierte, Avançsa, Asabys, Aliath and Vsquared. Merck KGaA added separate funding. The EIC grant was €2.49M.
imec, October 2024. Values in US$ millions.
What Cannot Be Checked
Questions for the EIC
How many patients have been treated with the graphene interface, when the 510(k) submission will be made, and how much the EIC Fund and Spanish public funds invested are not public.
Why Europe Should Care
INBRAIN is turning a European advanced material into a brain-computer interface product developed in Barcelona. The EIC helped fund the step into humans; EU and Spanish public investors are also among its shareholders.
What the project promised
A graphene cortical interface ready for first human use, on the path to commercial approval.
What the record shows
Animal and GLP studies, a first human procedure, a $50 million Series B, and no clearance yet.
The Verdict
Delivered, market still ahead
INBRAIN met the goals the EIC funded and drew large follow-on investment. Its first product still needs regulatory clearance before it can be sold.
INBRAIN Neuroelectronics and the EIC have not been asked for comment for this article. It is based entirely on public records and published statements, linked throughout.
Industry
HealthMedical devices
- Focus
- Neurology devices
- Technologies
- Brain-computer interfaces
- Graphene
- Keywords
- Parkinson's disease
- Neural interfaces
- Brain surgery
- Precision neurology