Neurinnov Ties EIC Accelerator Money to Restoring Hand Grasp

4 November 20261,865 words10 min

A complete spinal cord injury in the neck can leave a person unable to move the hands, and the EIC project summary says physiotherapy offers little hope of getting that movement back. Neurinnov, a 2018 spin-off of the French computer science institute Inria and the University of Montpellier, wraps electrodes around two nerves of the upper arm and uses a purpose-built chip to steer current to the bundles of fibres that close or open the hand. In small studies, patients have used it to hold a can and drink through a straw.

The EIC Accelerator selected Neurinnov's project ARCHE at its October 2025 cut-off for blended finance, and CORDIS records an EU contribution of €2,499,999 from 1 June 2026 to 31 May 2028. The money is meant to finish industrialising the implant, which CORDIS calls NeuriGrasp, run the pivotal clinical trial and obtain a CE mark in Europe and FDA approval in the United States. When Neurinnov raised its seed round in 2021, it announced that same pivotal study for 2024.

€2.5MEU contribution to ARCHE recorded in CORDIS
2Participants in each registered implant study so far
€0Revenue for 2025 in the national company directory

Company file

Legal entity
NEURINNOV SAS, SIREN 843 848 771, 73 allée Kléber, Montpellier; research site in Grabels
Registered
7 November 2018, initial capital €12,000, €25,399 since December 2021
Founders
David Andreu and David Guiraud per the company; Serge Renaux was the first president per the register
Management
Nicolas Serandour (president), David Andreu (managing director)
Investors
IRDI Capital Investissement, UI Investissement, Sofilaro (2021 seed); Mérieux Partners lists a 2021 seed investment
Staff
10 to 19 employees in 2024, per the national directory
EIC project
ARCHE, agreement 101297240, June 2026 to May 2028

Two electrodes instead of one per muscle

The usual approach to electrical stimulation of paralysed muscles, as the 2020 paper below frames it, places an electrode for each muscle. The Montpellier group's bet is that a nerve contains bundles of fibres that each serve a particular muscle, so a multi-contact cuff around the nerve can reach several muscles if the current is shaped precisely. A paper in the Journal of NeuroEngineering and Rehabilitation in May 2020, with David Guiraud listed under Neurinnov, reported tests during surgery on eight subjects: stimulating the radial and median nerves selectively produced isolated finger and thumb movements and key, power or hook grips, though different subjects reached different grips. The authors confirmed that the nerves contain muscle-specific bundles and set the goal of grasp and release with only two cuffs above the elbow. The work is registered as NCT03721861, a study at a Montpellier clinic from 2016 to 2019 that enrolled nine participants.

The current is steered by a dedicated chip. ERCIM News wrote in December 2021 that the technology combines epineural electrodes with a chip called SAFE for multipolar stimulation, is patented and licensed from the University of Montpellier and Inria, and has four further patents filed. In an August 2023 article published by Cadence Design Systems, whose software Neurinnov uses for the chip, the company put industrialisation at about 60% complete. The project summary in CORDIS describes the finished device as fully implantable, fitted in a two-hour operation and learned in two weeks of training, at a price it calls accessible; it gives no figure.

The clinical record

Two patients per implant study so far

Participants in the studies on ClinicalTrials.gov that name Neurinnov as a collaborator, plus the earlier intraoperative study by the same research group. Only the SENSORS figure is a target; the others are actual enrolment.

ClinicalTrials.gov records NCT03721861, NCT04306328, NCT05555914 and NCT07058506.

What the studies show

The clinical record is small. ClinicalTrials.gov lists a study sponsored by the Paris hospital group AP-HP with Inria and Neurinnov as collaborators, which implanted two cuff electrodes in two participants in Perpignan between October and December 2020 and kept them in place for one month. A Scientific Reports paper published on 6 October 2022, with three of its nine authors affiliated with Neurinnov, describes two participants whose grasp stayed stable over 28 days and who controlled the movements through voluntary actions to hold a can and drink through a straw. A follow-on study under the same name, AGILIS, sponsored by the Bouffard-Vercelli rehabilitation centre in Perpignan, ran from October 2022 to December 2023 and is recorded as completed with two participants, using cuffs on the median, ulnar and radial nerves. The 2020 study's registry entry has no results posted.

A third study, SENSORS, started in November 2024 and compares non-invasive interfaces, such as voice commands, motion sensors and switches, that a patient could use to tell the neuroprosthesis what to do; it plans 30 participants and was last updated in July 2025. A search of ClinicalTrials.gov for Neurinnov on 4 November 2026 returned only these three studies and no pivotal trial.

"Allows the stimulation of a sub-set of axons within a nerve"

David Guiraud, chief scientific officer, in ERCIM News, December 2021

The money before the Accelerator

Neurinnov raised €3 million in a seed round led by IRDI Capital Investissement, UI Investissement and Sofilaro, dated 9 December 2021 by Nordic9 and reported by CFNews on 27 December 2021 as a first round to continue clinical studies. Mérieux Partners separately lists a 2021 seed investment through its Pertinence Invest 2 fund, without an amount; the round reports above do not name it. ERCIM News added that the earlier clinical study, completed in 2020, had been funded by EIT Health.

The company has also worked on EU grants as a partner. In AI-HAND, an EIC Pathfinder project led by Inria from August 2023 to July 2027 to develop the implant's electronics and self-adapting electrodes, take it through animal studies and into a first human trial, CORDIS records €882,625 for Neurinnov out of €2,999,834. In DREIMS, an EIC Transition project led by Spain's national hospital for paraplegics on a spinal cord repair implant, Neurinnov supplies the implantable pulse generator and CORDIS records €748,750 for it.

The EU money

The Accelerator grant is larger than Neurinnov's two earlier EIC shares together

Neurinnov's own net EU contribution in each of the three Horizon Europe projects listed in CORDIS. AI-HAND and DREIMS are consortium projects led by others; ARCHE is Neurinnov's own. The equity part of the blended award is not public.

CORDIS project pages 101297240, 101099916 and 101136411. Values in € millions.

The register shows a company that is active and has no sales yet. The national company directory records Neurinnov as active, with a staff band of 10 to 19 employees in 2024, and for 2025 revenue of zero and a net loss of €439,487. The official commercial gazette BODACC lists 16 notices for the company, the latest the filing of its 2025 accounts published on 16 July 2026, and no insolvency proceeding. BODACC also records a new registration in March 2023 after the registered office moved from another court district (the 2021 accounts had been filed at the Béziers court), and two changes of president since 2023: David Guiraud took over from Serge Renaux in 2023, and Nicolas Serandour from Guiraud in January 2024. Staff figures for other years are not public in the sources reviewed, so whether the company has grown cannot be established.

The record

Eight years from a Montpellier lab to a pivotal trial that has yet to start

The clinical studies Neurinnov took part in so far implanted or tested the electrodes in small groups of patients; the pivotal study needed for a CE mark is the stated aim of the EIC project.

  1. Nov 2018Company registeredNeurinnov SAS created with €12,000 of capital, a spin-off of Inria and the University of Montpellier
  2. May 2020Intraoperative resultsJournal of NeuroEngineering and Rehabilitation paper on selective stimulation of the radial and median nerves in eight subjects
  3. Oct 2020First implant studyTwo participants, two cuff electrodes kept in place for one month, sponsored by AP-HP
  4. Dec 2021Seed roundLed by IRDI Capital Investissement, UI Investissement and Sofilaro; a pivotal study is announced for 2024€3M
  5. Oct 2022Scientific Reports paperTwo participants hold a can and drink through a straw; grasp stable over 28 days
  6. Aug 2023AI-HAND startsEIC Pathfinder project led by Inria; Neurinnov's share €882,625€0.88M
  7. Nov 2024SENSORS studyComparison of non-invasive control interfaces in Perpignan, 30 participants planned
  8. Feb 2026EIC selectionOne of 61 companies selected from the October 2025 cut-off, for blended finance
  9. Jun 2026ARCHE startsTwo-year EIC Accelerator project to finish industrialisation and run the pivotal trial€2.5M
  10. May 2028ARCHE endsScheduled end of the EIC projectScheduled

BODACC; ClinicalTrials.gov; Europe PMC; ERCIM News, 20 December 2021; Nordic9; CORDIS; EIC, 17 February 2026.

What ARCHE promised

The EIC's list of companies selected at the 1 October 2025 cut-off includes Neurinnov with ARCHE for blended finance, meaning a grant plus an equity investment. The cut-off drew 923 full applications, and the EIC announced 61 selected companies on 17 February 2026. CORDIS lists no total project cost. A web search on 4 November 2026 found no announced EIC Fund investment in Neurinnov, and the company does not appear on the EIC Fund's portfolio page.

The project's market case rests on figures it states itself: about 20 million people worldwide live with a spinal cord injury, some 40% of them at the cervical level, and nearly half of those injuries are complete. The project says European rehabilitation centres it is in contact with would take part in the pivotal trial and become the first customers, and it names stroke as a possible later use. None of these centres is named in CORDIS. The company's profile with MTEC Southern California describes the EIC grant the same way, as money for clinical, regulatory and industrial work ahead of an upcoming pivotal trial.

What the company said

A pivotal clinical study in Europe in 2024, needed for the CE mark (December 2021); with ARCHE, industrialisation, the pivotal trial and approval in Europe and the United States, with rehabilitation centres as first customers.

What the record shows

Two completed implant studies with two participants each and a 30-person interface study; no pivotal trial on ClinicalTrials.gov as of 4 November 2026; no revenue in 2025; ARCHE five months into a 24-month grant period.

  1. Selective grasp in patientsShown in small studiesTwo participants over 28 days, Scientific Reports, 2022.
  2. Finish industrialisationIn progressAbout 60% in August 2023, per the company; no later figure published.
  3. Pivotal clinical trialNot registeredAnnounced for 2024; no entry on ClinicalTrials.gov as of 4 November 2026.
  4. CE mark and FDA approvalPendingNo notified body review or FDA filing announced in the sources reviewed.

A European supply chain for a niche implant

The European dimension in the record is the supply chain of the implant itself. Neurinnov designs its own stimulation chip, and the AI-HAND consortium joins it with Inria, the University of Freiburg, the German company CorTec and rehabilitation centres in France and Luxembourg, per CORDIS. A CE mark for an implant like this falls under the EU Medical Device Regulation, which the DREIMS project names as the standard its own implant is being built to. The ARCHE period runs to May 2028, so the delivery of the pivotal trial cannot yet be judged; what can be checked is whether that trial appears in a registry in the coming months.

Verdict

Neurinnov rests on peer-reviewed work: papers from 2020 and 2022 by a Montpellier group on selective nerve stimulation, and grasping restored in a handful of patients. The weakness is time. The pivotal trial announced for 2024 is still not registered, the company had no revenue in 2025, and the stated purpose of the EIC grant is to take the device from two-patient studies to a CE mark.

The reporting is based on publicly available sources, listed below.

Industry

HealthMedical devices

Focus
  • Neurology devices
  • Assistive devices
Technologies
  • Neuromodulation
  • Implantable devices
  • Semiconductor design
Keywords
  • Spinal cord injury
  • Quadriplegia
  • Nerve stimulation
  • Neurorehabilitation