Qubit Pharmaceuticals: EIC Accelerator Money for Quantum Drug Design
Most drugs are still found by testing huge libraries of molecules in the lab. Computer simulation promises to narrow the search, but the physics of how a drug binds its target is expensive to compute accurately. Qubit Pharmaceuticals, founded in Paris in 2020 by five academics who spent years building molecular simulation software, is betting that faster supercomputing today, and quantum computing tomorrow, can make those calculations cheap enough to design drugs from scratch.
The European Innovation Council paid €2.5 million towards a €4.25 million project to build that platform, called Atlas. The project delivered software, papers, patents and preclinical drug leads. What it did not produce, and could not in two years, is a medicine in clinical trials.
Company file
- Legal entity
- Qubit Pharmaceuticals SAS, SIREN 883 649 238
- Founded
- May 2020, Paris
- Chief executive
- Robert Marino
- Scientific founders
- Jean-Philip Piquemal, Louis Lagardère, Matthieu Montes, Jay Ponder, Pengyu Ren
- Investors
- XAnge, Omnes, Quantonation, Octave Klaba
- EIC project
- ATLAS, 1 Sep 2022 to 31 Aug 2024, closed
- Funding type
- Blended finance (grant plus equity option)
- Staff
- 20 to 49 (register band)
What Qubit Pharmaceuticals Does Today
Qubit runs two businesses in one. The first is drug discovery: the company says it is building a pipeline of up to ten in-house programmes in oncology and inflammation, found with its own simulation platform. The second is quantum computing research, which it pursues through partnerships with the French quantum hardware company Pasqal, with national computing centres and, since April 2026, with Singapore's Centre for Quantum Technologies, to test quantum sampling algorithms on real hardware.
Its most visible quantum result is Hyperion, an emulator developed with Sorbonne University that the company says cuts by a factor of ten the number of qubits needed to simulate molecules. According to the CORDIS report, Hyperion was awarded €8 million from the France 2030 plan.
The Technology: Physics Before Chemistry
The key calculation in structure-based drug design is the binding free energy: how tightly a candidate molecule sticks to its protein target. Doing it accurately means simulating the motion of every atom, including the way electrons shift around each other, which is what polarisable force fields model. Qubit's founders built simulation software for exactly that over what their investor Omnes describes as more than 15 years of academic research. Atlas combines them with GPU supercomputing, machine learning for predicting toxicity, and quantum processors for the parts of the chemistry where classical computers struggle.
The efficiency claim
Binding-energy calculations four times cheaper
Cost of an absolute binding free energy (ABFE) calculation per compound, before and after the project's optimisations, as reported by the company.
CORDIS project 190141418, periodic report.
The EIC project reports that the cost of an absolute binding free energy calculation fell from €400 to €100 per compound, and that an AI model for absorption and toxicity reached "92% accuracy compared to experimental data". Both figures are the company's own.
What the EIC Project Promised, and What CORDIS Shows
The EIC project
The EU paid 59% of a €4.25M platform project
ATLAS ran from September 2022 to August 2024.
CORDIS project 190141418. Values in € millions.
ATLAS ran from 1 September 2022 to 31 August 2024 under the 2021 challenge for Strategic Digital and Health Technologies. Its goal was a "next generation HPC/QC in silico drug discovery platform for de novo design". The closing report lists six drug discovery projects launched in oncology and inflammation, preclinical leads across several chemical series against KAT6A, an oncology target, the integration of quantum processing units into the workflow, and a body of academic and intellectual property output.
The output
What two years of the EIC project produced
Counts reported in the CORDIS closing report. The drug programmes target oncology and inflammation; none has reached clinical trials.
CORDIS project 190141418, periodic report.
- A hybrid HPC and quantum design platformDeliveredPipeline automation, faster binding calculations and quantum processors integrated, per CORDIS.
- De novo drug candidatesPartialPreclinical leads against KAT6A; no candidate in clinical development.
- Intellectual propertyDeliveredEight patents and twelve papers reported.
- Quantum advantage in drug discoveryNot shownQuantum work remains at the emulator and algorithm stage.
What Has Happened Since
The record
Software, drug programmes and quantum emulators
Qubit Pharmaceuticals has used public money at every stage: an EIC grant, a France 2030 award and partnerships with national computing centres.
- May 2020Company foundedQubit Pharmaceuticals SAS, Paris, SIREN 883 649 238
- Jun 2021EIC Accelerator cut-offATLAS submitted under the Strategic Digital and Health Technologies challenge
- Jun 2022Seed roundXAnge, Omnes, Quantonation and OVH founder Octave Klaba€16.1M
- Sep 2022EIC project startsTwo years to build a hybrid HPC and quantum drug design platform€2.5M grant
- Aug 2024EIC project closesSix drug programmes, 12 papers, 8 patents, preclinical leads against KAT6A
- 2024Hyperion emulatorQuantum simulator project awarded France 2030 funding€8M
- Apr 2026Singapore collaborationResearch partnership with the Centre for Quantum Technologies
French company register via Societe.com and Pappers, CORDIS, Omnes Capital and The Quantum Insider.
The Money
Qubit raised a €16.1 million seed round in June 2022, bringing its total to €23 million since 2020, from XAnge, Omnes, Quantonation and OVH founder Octave Klaba. It then had 20 staff and planned to reach 60 across Paris and Boston.
The accounts reported by Societe.com, with 2023 matched by Pappers, show small revenues (€76,700 in 2023, €187,300 in 2024) and modest reported losses (€133,400 and €795,900); the public summary does not show how grants or research tax credits enter those figures. The notable change is on the balance sheet: debt rose from €3.7 million to €16.3 million in 2024 while equity fell from €3.5 million to €2.4 million.
The balance sheet
Debt jumped to €16.3M in 2024
Year-end values in € millions. Equity fell while debt more than quadrupled; the summary accounts do not say what the debt consists of.
Filed accounts via Societe.com.
A funding question for 2026
No equity round has been announced since the 2022 seed, and no EIC Fund investment has been made public. With equity at €2.4 million and debt at €16.3 million, the company's next financing, or a pharma partnership for one of its programmes, matters more than its next algorithm.
Why Europe Should Care
Qubit sits where two EU priorities meet: health technology and quantum computing. The Commission's Quantum Europe Strategy of July 2025 aims to make the EU a global quantum leader by 2030. A Paris company with founders from Sorbonne University, CNRS and the Conservatoire national des arts et métiers, working with French quantum hardware makers and national supercomputers, is the kind of European ecosystem the EIC wants to build.
What the project promised
A next-generation platform that uses supercomputers and quantum computers to design new drugs from scratch.
What the record shows
A working platform, patents, papers and preclinical leads, a quantum emulator backed by France 2030, and a balance sheet increasingly carried by debt, with no drug in the clinic.
The Verdict
Strong science, long road
ATLAS delivered measurable technical output, more than most EIC projects publish. But the real test for a drug discovery company is a drug, and no Qubit lead is in clinical development. Its quantum ambitions are further away still. The EU paid for a platform whose results are largely the company's own reports; whether it becomes a pharmaceutical business depends on financing and partnerships the public record does not yet show.
Qubit Pharmaceuticals has not been asked for comment for this article. It is based entirely on public records, company statements and EU project data, linked throughout.
Industry
HealthBiopharmaceuticals
AlsoDigital and computingQuantum technology
- Focus
- Drug discovery platforms
- Quantum software
- Technologies
- Molecular simulation
- High-performance computing
- Quantum algorithms
- Keywords
- Oncology
- Inflammation
- Binding free energy
- Computational drug design