SIT Sordina and the EIC Accelerator: FLASH Radiotherapy Waits

30 September 2026883 words5 min

S.I.T. - Sordina IORT Technologies, registered in Rome with a factory in Aprilia, makes small mobile electron accelerators that deliver radiotherapy inside the operating room while a tumour bed is exposed. Its EIC project, LIACFLASH, added the ability to deliver FLASH radiotherapy, an ultra-high dose rate that in research "enables delivery of high radiation dose with significantly reduced associated radiocytotoxicity" to healthy tissue, according to CORDIS.

The European Innovation Council granted €2,499,963 towards a €3.57 million project from December 2022 to May 2025. The final report says SIT designed and validated "the first medical linear accelerator (LINAC) capable of delivering both conventional and FLASH dose-rate electron radiotherapy" for surgery, reached TRL 8, built an AI-assisted planning unit and did pre-compliance testing against safety standards. It launched a contest to lend a system to a European clinic and said talks with strategic partners had begun "although formal agreements are still under evaluation". At ESTRO 2026 SIT described FLASH as "ongoing" development alongside its conventional LIAC HWL machine, according to its announcement.

€2.50MEIC grant, 70% of a €3.57M project
TRL 8Reached in May 2025
14Scientific papers during the project
0Patients treated with FLASH announced

Company file

Legal entity
S.I.T. - Sordina IORT Technologies S.p.A., registered office Rome
Factory
Aprilia (Latina)
CEO
Renato Cervo
Products
LIAC HWL (IOeRT), ElectronFlash (research), LIACFLASH
Research partners
Institut Curie, AtOMKI, University of Catania
EIC project
1 Dec 2022 to 31 May 2025
EIC funding
Grant first

Where SIT Stands Now

SIT's recent news concerns its established machines and research platforms: a first intraoperative procedure with LIAC HWL at a hospital in Elche, Spain, in March 2026, an ElectronFlash system chosen by the University of Catania for glioblastoma research, and a research agreement with AtOMKI. In March 2026 its LIAC FLASH GT project was admitted for funding by the Italian business ministry's Sustainable Growth Fund, according to the company. SIT's ESTRO 2026 materials name a "CHC FlashPrime" platform for ultra-high dose rates as the next step towards clinical FLASH.

The record

A FLASH radiotherapy machine built, not yet in patients

SIT's EIC project took its LIACFLASH accelerator to TRL 8 in May 2025. In 2026 the company still described FLASH as under development and validation, alongside its conventional intraoperative machines.

  1. 2019Institut Curie partnershipElectronFlash research platform
  2. Jun 2022EIC Accelerator cut-offLIACFLASH intraoperative FLASH systemgrant first
  3. Dec 2022EIC project starts€3.57M project€2.50M grant
  4. 2025Patents filedThree applications: accelerator, AI planning, safety
  5. May 2025EIC project endsTRL 8; contest to loan a system to a clinic
  6. Mar 2026LIAC FLASH GTAdmitted for Italian ministry funding
  7. May 2026ESTRO 2026FLASH presented as "ongoing" development

CORDIS, Institut Curie and SIT.

"Initial conversations with potential strategic partners were initiated, and early co-investment interest has been registered, although formal agreements are still under evaluation."

S.I.T. - Sordina IORT Technologies, final report to the EIC

The Technology: Radiation in a Flash

FLASH radiotherapy delivers a dose at rates far above conventional treatment; the project says this widens the therapeutic window by harming healthy tissue less while still killing tumour cells. SIT has worked with Institut Curie since 2019, building the ElectronFlash research platform at Curie's Orsay site for in vitro and preclinical studies. LIACFLASH is meant to bring this into the operating room, and also to treat superficial tumours through the skin, without shielding the room.

The EIC project

Outputs listed in the final report

Counts from the report. The technology readiness level reached is shown for scale.

CORDIS project 190151856, final report.

What the EIC Project Promised, and What CORDIS Shows

The EIC project

The EU paid 70% of a €3.6M project

LIAC FLASH ran from December 2022 to May 2025. CORDIS still lists it as signed.

CORDIS project 190151856. Values in € millions.

The project promised a LIACFLASH system for cancer treatment, and the report documents a validated TRL 8 machine with planning software and three new patent applications. Moving it to patients requires certification and clinical trials, neither of which is reported as done. CORDIS still lists the project as signed.

  1. FLASH-capable IOeRT linacDeliveredTRL 8.
  2. AI planning unitDeliveredPer final report.
  3. Regulatory compliancePre-complianceNo certification reported.
  4. Clinical useNot yetNo FLASH patients.

The Money

SIT has not published revenue figures, and its Italian filings are not freely available online. The report says co-investment interest was registered but no agreement was reached by the end of the project. No EIC Fund investment has been announced; the award was grant first.

The context

The cancer burden the project cites

Global figures for 2020 as given in the EIC report, in millions. The report adds that about two in three cancer patients receive radiation therapy.

CORDIS project 190151856, final report.

What Cannot Be Checked

Questions for the EIC

When LIACFLASH will be certified, which clinic won the loan system, whether a strategic partner signed and SIT's revenue are not public.

Why Europe Should Care

The report says about two in three cancer patients receive radiotherapy. SIT is a European manufacturer of the accelerators that could deliver it. The EIC paid for the machine; the clinical proof is still ahead.

What the project promised

An intraoperative radiotherapy system able to deliver both conventional and FLASH doses for cancer treatment.

What the record shows

A TRL 8 machine, patents and papers, and FLASH still described as under development in 2026.

The Verdict

Machine ready, medicine not

SIT says it built the FLASH-capable accelerator the EIC funded. Until it is certified and tested in patients, the promise of gentler, stronger radiotherapy remains a research result.

SIT and the EIC have not been asked for comment for this article. It is based entirely on public records and published statements, linked throughout.

Industry

HealthMedical devices

Focus
  • Oncology devices
Technologies
  • Radiation therapy technology
Keywords
  • FLASH radiotherapy
  • Intraoperative radiotherapy
  • Oncology
  • Radiotherapy
  • Particle accelerators