SolasCure and the EIC Accelerator: A Maggot Enzyme for Wounds

30 September 2026942 words5 min

SolasCure, founded in 2017 as a spin-off of the German company BRAIN Biotech and based in Cambridge, UK, develops Aurase Wound Gel, a hydrogel containing tarumase, a recombinant enzyme originally cloned from medical maggots, which removes dead tissue from chronic wounds such as venous leg ulcers without causing pain. In November 2023 it announced it had been "selected to receive European Innovation Council (EIC) funding" from the June 2023 Accelerator cut-off, one of 47 companies and three in the UK, according to SolasCure. The award was a grant only. SolasCure does not appear in CORDIS, the EU's project database, so the project's budget, dates and reports are not public.

SolasCure completed its second Phase II trial, CLEANVLU2, in patients with treatment-resistant venous leg ulcers in February 2026. At higher enzyme concentrations, after 26 days, the gel achieved "65% debridement versus 9% in control (p=0.005) and 58% wound area reduction versus 15% in control (p=0.022)", with no additional pain, according to SolasCure. The company has said a further, longer Phase II study will come before confirmatory Phase III trials. It also received Fast Track designation from the US Food and Drug Administration for calciphylaxis ulcers in 2025.

65% vs 9%Debridement at 26 days, gel vs control
58% vs 15%Wound area reduction
9Average employees, 2025/26
£113,155Cash, June 2026

Company file

Legal entity
SolasCure Limited, company 10826246, Cambridge
Origin
Spin-off from BRAIN Biotech AG, 2017
Product
Aurase Wound Gel (tarumase)
Investors
Seneca Partners, BRAIN Biotech, EVA Pharma, Jonathan Milner, Wealth Club
Other public funding
Innovate UK Biomedical Catalyst, £405K
US status
FDA Fast Track, calciphylaxis ulcers
EIC funding
Grant only

Where SolasCure Stands Now

SolasCure's accounts for the year to June 2026 show cash of £113,155, down from £810,344 a year earlier and £1.87 million in 2023, net assets of £3.51 million, and nine employees on average, according to filings at Companies House. It allotted new shares in December 2024 and September 2025, and filed director changes in 2025 and 2026. It has collaborated with the US Army Institute of Surgical Research on combat wound care. No new funding round or partnership deal has been announced since the trial results.

The record

From maggot enzyme to a completed Phase II trial

SolasCure completed its second Phase II trial of Aurase Wound Gel in 2026, after being selected by the EIC in 2023. Its cash fell to £113,155 by June 2026.

  1. 2017SolasCure foundedSpin-off from BRAIN Biotech AG
  2. Mar 2023£10.9M Series BLed by Seneca Partners
  3. Jun 2023EIC Accelerator cut-offAurase Wound Gelgrant only
  4. Dec 2023Phase IIa resultsSafety, pain-free application
  5. Mar 2024£405K Innovate UK grantBiomedical Catalyst
  6. Mar 2025CLEANVLU2 startsHigher enzyme dose
  7. Jun 2025FDA Fast TrackCalciphylaxis ulcers
  8. Feb 2026CLEANVLU2 completedFaster debridement and healing

SolasCure and Companies House.

"This grant will propel the ongoing development of Aurase Wound Gel."

SolasCure, on its EIC selection, November 2023

The Technology: Borrowing From Maggots

Chronic wounds affect around 100 million people globally, and after six weeks of standard care as few as 41% close, according to SolasCure. Dead tissue in the wound slows healing, and removing it surgically or with existing products is often painful. Maggots have long been used to clean wounds; SolasCure cloned one of their enzymes, which targets fibrin, collagen and elastin, and put it in a gel. The company says it also activates receptors involved in tissue repair.

The results

CLEANVLU2 after 26 days: Aurase against standard care

At higher enzyme doses, Aurase Wound Gel removed 65% of dead tissue against 9% for standard care, and wound area fell 58% against 15%, SolasCure reports.

SolasCure, CLEANVLU2 results (February 2026). Percent.

What the EIC Award Promised, and What the Record Shows

The EIC selected SolasCure to develop Aurase Wound Gel, but because the company is not in CORDIS, what exactly the project promised and whether it reported completion are not public. The clinical record since 2023 is positive: a successful Phase IIa, a larger Phase II with statistically significant results, and an FDA Fast Track designation. Confirmatory Phase III trials, needed for approval, have not started.

  1. Phase II efficacy dataDeliveredCLEANVLU2, February 2026.
  2. Regulatory progressStartedFDA Fast Track, 2025.
  3. EIC project reportingUnverifiedNot in CORDIS.
  4. Financing for Phase IIINot announcedCash £113,155.

The Money

SolasCure raised a £10.9 million Series B in March 2023 led by Seneca Partners, according to SolasCure, and a £405,000 Innovate UK Biomedical Catalyst grant in March 2024. The amount of its EIC grant has not been published by the company. Its falling cash means it needs new money to reach Phase III.

The accounts

Cash and net assets at each June year end

SolasCure's cash fell from £1.87 million in June 2023 to £113,155 in June 2026, and its net assets shrank each year.

Companies House, SolasCure Limited annual accounts. Values in £ millions.

What Cannot Be Checked

Questions for the EIC

How much SolasCure received, whether it was paid by the EU or by Innovate UK under the UK's Horizon Europe arrangements, what the project promised and whether it was completed are not public.

Why Europe Should Care

Chronic wounds are common, painful and expensive, and treatment has changed little. A pain-free gel that cleans and heals faster could help millions. SolasCure has strong Phase II data; it needs a partner or investors to reach Phase III, and its accounts show little room to wait.

What the award promised

Development of a biomimetic enzyme gel to treat chronic wounds.

What the record shows

Positive Phase II results and FDA Fast Track, with no public project report and almost no cash.

The Verdict

Good data, thin wallet

SolasCure's science moved forward after its EIC selection. Its cash has fallen to £113,155 and it has announced no new funding.

SolasCure and the EIC have not been asked for comment for this article. It is based entirely on public records and published statements, linked throughout.

Industry

HealthBiopharmaceuticals

Focus
  • Recombinant proteins
Technologies
  • Protein engineering
Keywords
  • Chronic wounds
  • Venous leg ulcers
  • Wound debridement
  • Wound care