SolasCure and the EIC Accelerator: A Maggot Enzyme for Wounds
SolasCure, founded in 2017 as a spin-off of the German company BRAIN Biotech and based in Cambridge, UK, develops Aurase Wound Gel, a hydrogel containing tarumase, a recombinant enzyme originally cloned from medical maggots, which removes dead tissue from chronic wounds such as venous leg ulcers without causing pain. In November 2023 it announced it had been "selected to receive European Innovation Council (EIC) funding" from the June 2023 Accelerator cut-off, one of 47 companies and three in the UK, according to SolasCure. The award was a grant only. SolasCure does not appear in CORDIS, the EU's project database, so the project's budget, dates and reports are not public.
SolasCure completed its second Phase II trial, CLEANVLU2, in patients with treatment-resistant venous leg ulcers in February 2026. At higher enzyme concentrations, after 26 days, the gel achieved "65% debridement versus 9% in control (p=0.005) and 58% wound area reduction versus 15% in control (p=0.022)", with no additional pain, according to SolasCure. The company has said a further, longer Phase II study will come before confirmatory Phase III trials. It also received Fast Track designation from the US Food and Drug Administration for calciphylaxis ulcers in 2025.
Company file
- Legal entity
- SolasCure Limited, company 10826246, Cambridge
- Origin
- Spin-off from BRAIN Biotech AG, 2017
- Product
- Aurase Wound Gel (tarumase)
- Investors
- Seneca Partners, BRAIN Biotech, EVA Pharma, Jonathan Milner, Wealth Club
- Other public funding
- Innovate UK Biomedical Catalyst, £405K
- US status
- FDA Fast Track, calciphylaxis ulcers
- EIC funding
- Grant only
Where SolasCure Stands Now
SolasCure's accounts for the year to June 2026 show cash of £113,155, down from £810,344 a year earlier and £1.87 million in 2023, net assets of £3.51 million, and nine employees on average, according to filings at Companies House. It allotted new shares in December 2024 and September 2025, and filed director changes in 2025 and 2026. It has collaborated with the US Army Institute of Surgical Research on combat wound care. No new funding round or partnership deal has been announced since the trial results.
The record
From maggot enzyme to a completed Phase II trial
SolasCure completed its second Phase II trial of Aurase Wound Gel in 2026, after being selected by the EIC in 2023. Its cash fell to £113,155 by June 2026.
- 2017SolasCure foundedSpin-off from BRAIN Biotech AG
- Mar 2023£10.9M Series BLed by Seneca Partners
- Jun 2023EIC Accelerator cut-offAurase Wound Gelgrant only
- Dec 2023Phase IIa resultsSafety, pain-free application
- Mar 2024£405K Innovate UK grantBiomedical Catalyst
- Mar 2025CLEANVLU2 startsHigher enzyme dose
- Jun 2025FDA Fast TrackCalciphylaxis ulcers
- Feb 2026CLEANVLU2 completedFaster debridement and healing
SolasCure and Companies House.
"This grant will propel the ongoing development of Aurase Wound Gel."
SolasCure, on its EIC selection, November 2023The Technology: Borrowing From Maggots
Chronic wounds affect around 100 million people globally, and after six weeks of standard care as few as 41% close, according to SolasCure. Dead tissue in the wound slows healing, and removing it surgically or with existing products is often painful. Maggots have long been used to clean wounds; SolasCure cloned one of their enzymes, which targets fibrin, collagen and elastin, and put it in a gel. The company says it also activates receptors involved in tissue repair.
The results
CLEANVLU2 after 26 days: Aurase against standard care
At higher enzyme doses, Aurase Wound Gel removed 65% of dead tissue against 9% for standard care, and wound area fell 58% against 15%, SolasCure reports.
SolasCure, CLEANVLU2 results (February 2026). Percent.
What the EIC Award Promised, and What the Record Shows
The EIC selected SolasCure to develop Aurase Wound Gel, but because the company is not in CORDIS, what exactly the project promised and whether it reported completion are not public. The clinical record since 2023 is positive: a successful Phase IIa, a larger Phase II with statistically significant results, and an FDA Fast Track designation. Confirmatory Phase III trials, needed for approval, have not started.
- Phase II efficacy dataDeliveredCLEANVLU2, February 2026.
- Regulatory progressStartedFDA Fast Track, 2025.
- EIC project reportingUnverifiedNot in CORDIS.
- Financing for Phase IIINot announcedCash £113,155.
The Money
SolasCure raised a £10.9 million Series B in March 2023 led by Seneca Partners, according to SolasCure, and a £405,000 Innovate UK Biomedical Catalyst grant in March 2024. The amount of its EIC grant has not been published by the company. Its falling cash means it needs new money to reach Phase III.
The accounts
Cash and net assets at each June year end
SolasCure's cash fell from £1.87 million in June 2023 to £113,155 in June 2026, and its net assets shrank each year.
Companies House, SolasCure Limited annual accounts. Values in £ millions.
What Cannot Be Checked
Questions for the EIC
How much SolasCure received, whether it was paid by the EU or by Innovate UK under the UK's Horizon Europe arrangements, what the project promised and whether it was completed are not public.
Why Europe Should Care
Chronic wounds are common, painful and expensive, and treatment has changed little. A pain-free gel that cleans and heals faster could help millions. SolasCure has strong Phase II data; it needs a partner or investors to reach Phase III, and its accounts show little room to wait.
What the award promised
Development of a biomimetic enzyme gel to treat chronic wounds.
What the record shows
Positive Phase II results and FDA Fast Track, with no public project report and almost no cash.
The Verdict
Good data, thin wallet
SolasCure's science moved forward after its EIC selection. Its cash has fallen to £113,155 and it has announced no new funding.
SolasCure and the EIC have not been asked for comment for this article. It is based entirely on public records and published statements, linked throughout.
Industry
HealthBiopharmaceuticals
- Focus
- Recombinant proteins
- Technologies
- Protein engineering
- Keywords
- Chronic wounds
- Venous leg ulcers
- Wound debridement
- Wound care