UVERA's Bacterial Sunscreen: EIC Accelerator Grant, Low Yields

15 October 20262,311 words12 min

A sunscreen sold in the EU may only use UV filters that the EU has approved one by one. UVERA, a start-up from Łódź, set out to add a natural one: scytonemin, a brown pigment that cyanobacteria have used as a sun shield for about two billion years, as the company told the European Investment Bank. In the Green Deal round of the EIC Accelerator pilot in May 2020, the European Commission selected the company for a grant to build a pilot plant and register the ingredient. The pilot plant ran. The pigment yield did not reach the level an industrial plant needs, and six years after selection the filter is still not on the EU's list of permitted UV filters.

UVERA was selected at the 19 May 2020 cut-off, according to the Commission's list of selected Green Deal projects, which names the company alone, with no partner companies. The grant agreement for the project, also called UVERA, was signed on 22 September 2020; the EU contributed €2,493,163.75 to a total cost of €3,561,662.50, and the project ran from 1 October 2020 to 30 June 2024, according to CORDIS. EIT Health, which had accelerated the company, reported the award as €2.5 million in August 2020.

€2.49MEU grant, EIC Accelerator pilot, May 2020
€3.56MTotal project cost, October 2020 to June 2024
€3.5M+Raised in total for R&D, per the company's final report
Not listedScytonemin in the EU cosmetics ingredient database

Company file

Legal entity
UVERA Spółka Akcyjna (joint-stock company), KRS 0000762259, NIP 7252285112
Founded
Articles signed 5 November 2018; registered 12 December 2018
Headquarters
ul. Dr. Jana Muszyńskiego 2, Łódź, Poland
Leadership
Magdalena Jander (CEO, president of the management board); Adam Kiciak (CMO, board member); Jacek Wierzchos (co-founder, scientist)
Share capital
PLN 180,850, fully paid, since January 2022
Branches
Huelva (Spain) and Gutkowo (Poland), both deleted from the register in October 2024
Staff
11 to 50, per EMIS (2025); no exact figure public
EIC project
UVERA, CORDIS 101009401, grant only, closed June 2024
EIC Fund
Not in the EIC Fund portfolio

Where UVERA Stands Now

UVERA is still a registered, active company. The full extract from Poland's National Court Register (KRS) shows no liquidation, insolvency or restructuring entry, and records that the company filed its audited 2025 accounts, the auditor's report, the shareholders' approval and a management report on 29 June 2026. It has filed accounts every year since its first financial year, which ran from November 2018 to December 2019. The management board has had the same two members since registration; the register masks their names, but its initials and roles match Magdalena Jander, president, and Adam Kiciak, whom the website names as the management board.

The same register shows a company that has contracted. In October 2024, four months after the EIC project ended, UVERA deleted both of its registered branches: one in Huelva, in south-west Spain, and one in Gutkowo, near Olsztyn in north-east Poland. The company website still lists the Huelva address as a branch office, and its news section stops in May 2022. The register extract does not contain the accounts themselves, and the official financial-statement repository could not be accessed for this article. The data provider EMIS, which shows only percentage changes for free, reports that between the two latest years it holds, total assets fell by 51.68% and total equity by 964.28%, while net sales rose by 90.95%. A fall in equity of more than 100% from a positive starting value means equity turned negative; the absolute figures could not be verified, and EMIS gives both "2025" as its latest financial year and 15 April 2025 as its last update.

The record

Prizes came fast, the biofactory did not

UVERA collected start-up awards in 2019 to 2021. Its EIC project ended in June 2024 with the industrial plant redesigned, and the company's two branches were deleted from the register four months later.

  1. Nov 2018Company foundedArticles of association signed for UVERA S.A., Łódź
  2. Dec 2018RegisteredEntered in the National Court Register, KRS 0000762259
  3. Nov 2019EIT Health InnoStars AwardFirst prize at the grand final in Hamburg
  4. May 2020EIC Accelerator pilot cut-offSelected among the Green Deal projectsgrant only
  5. Oct 2020Project starts€2.49M EU contribution to a €3.56M project
  6. Dec 2020EIT Health CatapultWins the biotech category
  7. May 2021Patent priorityStrains, culture process and a form of scytonemin
  8. Jan 2022Share capital raisedTo PLN 180,850, registered in KRS
  9. 2023Polish Challenge FundUSD 40,000 to test biomass fertiliser in Georgian vineyards
  10. Jun 2024EIC project endsPilot yields too low for the planned biofactory
  11. Oct 2024Branches deletedHuelva (Spain) and Gutkowo (Poland) removed from KRSdownsizing
  12. Jun 20262025 accounts filedAudited accounts and management report in KRS

Polish National Court Register (KRS), CORDIS, European Commission winner list, EIT, EIB and the UVERA website.

The Technology: A Sun Shield From Desert Bacteria

Scytonemin is a yellow-brown pigment that some cyanobacteria build into their outer sheath to absorb ultraviolet light. A 2021 review in Marine Drugs describes it as "a promising UV-screen and antioxidant small molecule with commercial value in cosmetics and medicine" that is made only by some cyanobacteria. The same review shows the difficulty: in one species, the dry-weight ratio of sheath sugars to scytonemin was estimated at about 100 to 1, and, the authors wrote, enhanced production through metabolic engineering "has not been reported". They list growing the cells first and stressing them to produce pigment later, so-called two-stage cultivation, as a standard strategy.

UVERA's approach was to isolate wild strains from extreme environments, a field in which co-founder Jacek Wierzchos had worked, grow them without genetic modification in closed tube reactors, then expose them to UV light so that they produce the pigment, according to the project's final report. The company pitched the process as running on sunlight and CO2, with oxygen and a biomass that could be sold as fertiliser as by-products. Its patent application, WO 2022/250557, filed with a Polish priority date of 28 May 2021, covers the isolation and culture of the strains, their growth media and "a form of scytonemin". Google Patents lists national filings in at least 13 jurisdictions, including a European application still pending and a Spanish utility model for "scytonemin crystals" granted in January 2025.

"It's quite comfortable working with a product that was created by evolution because we are not working with something synthetic."

Adam Kiciak, chief medical officer and co-founder, to the European Investment Bank, December 2021

The commercial case rests on the safety record of existing filters. UVERA's materials say synthetic filters can disrupt hormones, damage DNA and harm coral reefs. These are the company's claims and are not tested here. What is not disputed is the barrier to market: in the EU, a cosmetic product may only contain UV filters listed in Annex VI of the Cosmetics Regulation, under Article 14 of Regulation (EC) No 1223/2009. A search of the Commission's CosIng database on 15 October 2026 returned no entry for scytonemin at all, while established filters such as bemotrizinol appear with their Annex VI reference.

What the EIC Project Promised, and What CORDIS Shows

When the grant was announced, Jander said it would pay for a pilot bioproduction plant and for "full certification and registration of the product", according to MamStartup; AIN reported the same two goals. The CORDIS objective went further: to offer the cosmetics market a natural UV protector produced "on industrial scale". In December 2021 the company told the EIB it was producing the molecule "in small amounts", testing it in formulations with some cosmetics companies, and building a pilot factory, with a plan to license the molecule rather than manufacture at scale.

The project budget

The EU paid 70% of the €3.56M UVERA project

UVERA was the only beneficiary. The company had to fund the remaining €1.07M itself.

CORDIS, project 101009401. Values in € millions.

The final report, covering October 2021 to June 2024, is unusually frank. The company scaled up biomass production in closed reactors and defined the assumptions for the engineering design of an industrial "Biofactory". But lab-scale data had suggested "a promising yield of scytonemin", and at semi-industrial scale "the scytonemin yield was lower than anticipated". Multiple validation trials, the report says, "confirmed that the industrial-scale production would not meet the necessary yield requirements". The company then dropped the two-stage process and switched to applying UV stress during cultivation, a method that "potentially" improves yields. Extraction and purification at scale "proved to be complex". A formula based on the pigment showed absorbance in the UVA and UVB range comparable to SPF 30 and 50 products in the lab, but the report says further studies are needed to standardise the measurement, and that dermatological and clinical testing protocols were "planned", not run. It records one licensing agreement "for further development of scaling-up" without naming the partner. The project ended on its CORDIS end date; whether that date had been extended is not public.

  1. Pilot bioproduction plantDeliveredPhotos of the pilot plant and tube reactors in operation in the final report.
  2. Patent protectionDeliveredPCT application WO 2022/250557; Spanish utility model granted January 2025.
  3. Industrial-scale productionNot achievedYields too low for the planned biofactory; process redesigned.
  4. Certification and registrationNot achievedNo entry for scytonemin in CosIng; clinical tests only planned.
  5. Ingredient sold to cosmetics brandsNot achievedNo product, customer or supply deal announced.
  6. Licensing partnerPartlyOne licensing agreement reported; partner and terms not public.

What the company said

A natural UV protector produced "on industrial scale" for the first time, certified and registered with EU money, and supplied to the cosmetics industry.

What the record shows

A working pilot plant and a patent family, but yields too low for industrial production, no EU approval as a UV filter, no named customer, and two branches closed in 2024.

What UVERA Has Achieved Since the Award

Most of UVERA's public recognition came early. It won the EIT Health InnoStars Awards in November 2019 and the biotech category of EIT Health Catapult in December 2020, and was a finalist in the EIB Institute's Social Innovation Tournament in 2021, according to the company website and the EIB. Before applying, it received a Polish "Eurogrant" of PLN 280,060 to prepare its EIC Accelerator application, its website says.

Its share capital grew from PLN 141,100 at registration to PLN 162,265 in September 2020 and PLN 180,850 in January 2022, the register shows; no increase has been registered since. The issue price of the new shares, and so the amount raised, is not in the extract. The final CORDIS report says the company had raised "over EUR 3.5 million" in total for R&D and pilot prototyping and was "now fundraising to scale up production". No funding round has been announced since, and the EU's EIC Fund portfolio does not list UVERA, which is consistent with its grant-only award.

The shares

Two share issues, both before the pilot results

Registered share capital, at PLN 1 per share. The last increase was registered in January 2022; none has been registered since.

Polish National Court Register (KRS), full extract for KRS 0000762259. Values in PLN thousands.

The one new project made public since the grant uses the by-product, not the sunscreen. In 2023 UNDP's Polish Challenge Fund backed a USD 40,000 project to test UVERA's cyanobacterial biomass as fertiliser for vineyards in Georgia, with the local partner Euphoria Wines, according to a press release on the company's site. Its results have not been published. No peer-reviewed paper with a UVERA affiliation on scytonemin could be found.

The yield problem

Scytonemin's appeal is that nature already makes it; its weakness is that nature makes very little of it. UVERA's own report concedes that the yields seen in the lab did not hold at semi-industrial scale. Whether a biofactory can pay at these yields, and whether the company will fund the safety dossier an EU UV filter needs, is not stated in any document found for this article.

Why Europe Should Care

The EIC chose UVERA in its first Green Deal round, and the project fits the EU's environmental agenda. The Commission's Zero Pollution Action Plan, adopted on 12 May 2021, aims to cut pollution of air, water and soil to levels no longer harmful to health and ecosystems by 2050, with the Chemicals Strategy for Sustainability as a headline action against hazardous chemicals. A biologically produced UV filter, made in Europe without synthetic chemistry, would serve both aims and give European cosmetics makers an ingredient that does not depend on chemical supply chains.

The case also shows the limits of a 45-month grant for this kind of product. A new UV filter needs both an economic production process and a full safety assessment before it can be sold in the EU, and UVERA's grant ended with the first still unsolved. That is a fair outcome for a high-risk biotech project; the gap is that, two years after the project closed, nothing public shows how the company plans to close it.

The Verdict

A real pilot, an unsolved yield

UVERA did what the grant could pay for most directly: it built and ran a pilot plant, protected its strains and process, and reported its setbacks plainly. It did not reach industrial production, did not register its filter, and has announced no customer. The company is still filing accounts, but it has shed its branches, and the register and EMIS data point to a smaller company than the one the EIC funded.

UVERA has not been asked for comment for this article. It is based entirely on public records, company statements and EU project data, linked throughout.

Industry

Materials and chemicalsPersonal care ingredients

Focus
  • UV filters
Technologies
  • Cyanobacteria cultivation
  • Photobioreactors
Keywords
  • Scytonemin
  • Sunscreen
  • Natural UV filters
  • Cosmetics